What are the common symptoms of PNH?
Low hemoglobin (chronic anemia)
Anemia is a result of low red blood cell count or low hemoglobin levels. When it becomes chronic, it can impact organ function and lead to other complications.
Fatigue
Fatigue can affect people to varying degrees. Generally, it can be felt as diminished energy levels and slowness that can interfere with everyday life. For some people, fatigue may not interfere with their daily routines, but for others, it can impact their performance at work, or even reduce their quality time with loved ones.
Transfusion dependence
Blood transfusions can be used to increase hemoglobin levels as a treatment for anemia. If required over the long term, this is called transfusion dependence and can result in high iron levels (iron overload), which may damage the organs over time.